Nippon Shokubai: Development of a coating material with a strong antiviral effect! – Inactivation of the human coronavirus thanks to the new coating material –

January 7, 2022

NIPPON SHOKUBAI CO., LTD. (Headquarters: Osaka, Japan, President: Yujiro Goto, hereinafter “Nippon Shokubai”), and a research group led by Professor Hiroshi Uyama of the Division of Applied Chemistry, Graduate School of Engineering, Osaka University jointly developed a coating material which is expected to add antibacterial and antiviral effects to the surfaces of various materials.

This coating material
â–  has the antibacterial and antiviral effects of the metal phthalocyanine complex and the adhesive function of cellulose acetate,
â–  inactivated more than 99.9% of a human coronavirus,
â–  should be used for a wide range of applications which require hygienic measures, and
â–  was developed by Nippon Shokubai Research Alliance Laboratories established by us at the Graduate School of Engineering at Osaka University in April 2017.

The newly developed coating material consists of a metal complex of phthalocyanine (* 1) and cellulose acetate, and exhibits the antibacterial and antiviral effects of the metal phthalocyanine complex and the adhesion function of cellulose acetate to various materials.
In a comparative evaluation of existing photosensitizers (* 2) with a focus on photosensitizers that generate singlet oxygen capable of inactivating various bacteria, fungi and viruses, we found that the phthalocyanine metal complex was optimal in terms of singlet oxygen release capacity and stability. In addition, by optimizing the structure of phthalocyanine through the full use of design technology for infrared cut filter pigments, etc. that Nippon Shokubai has accumulated in the past, we have developed a new metal phthalocyanine complex which is highly dispersible in cellulose acetate and can produce singlet oxygen over a long period of time.

Cellulose acetate is a polymer obtained by modifying cellulose of plant origin with acetic acid, and can be used to form a layer of cellulose acetate on the surfaces of various different materials such as glass and glass. PTFE (polytetrafluoroethylene, which is a fluororesin) by coating the surface with its polymer solution and drying.

It was confirmed that over 99.9% of the human coronavirus was inactivated when we evaluated the antiviral performance of PMMA (acrylic resin) plates coated with the developed product against human coronavirus OC43 with the test method specified in the ISO standard. 21702 (* 3).

Based on the above, the developed product is expected to be widely used as a coating material with antibacterial and antiviral effects for applications requiring hygiene measures.

Going forward, Nippon Shokubai Research Alliance Laboratories will continue to promote the creation of innovative technologies, the creation of new companies and the development of human resources for research by integrating the cutting-edge academic findings and IT infrastructure of the Graduate School of Engineering. , Osaka University with Nippon Shokubai’s proprietary technologies, including catalysts, organic synthesis and polymer synthesis, and using data science.

* 1 Phthalocyanine is a cyclic compound with a structure in which the 4 phthalate imides are crosslinked by nitrogen atoms. The complex is formed by the formation of a complex between it and metal ions.
* 2 A substance that helps the reaction and emission process of light by transferring the energy obtained by absorbing light to other substances.
* 3 Under the care of VisGene, Ltd.

This press release does not claim that the product developed is effective against all bacteria and viruses. In addition, it does not claim to be effective in preventing or treating any disease.

About NIPPON SHOKUBAI Co., Ltd. : Since 1941, Nippon Shokubai has developed its business with unique catalyst technology. Nippon Shokubai supplied, for example, ethylene oxide, acrylic acid, automotive catalysts, process catalysts, etc. Of all of them, our global superabsorbent polymer market share is currently the largest in the world. Nippon Shokubai is a global chemical company operating under its corporate mission “To provide technological equipment to the wealth and comfort of people and society through our unique technology”.

Corporate Communications Department,
TEL: + 81-3-3506-7605 E-mail: [email protected]

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